Efficient Synthesis of Novel 3-Substituted Coumarin-3-carboxamide 


Vol. 58,  No. 2, pp. 186-192, Apr.  2014
10.5012/jkcs.2014.58.2.186


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  Abstract

A series of novel pseudopeptides contained coumarin skeleton were synthesized through the Ugi-four-component reaction. The 3-substituted coumarin-3-carboxamides were formed through reaction of benzaldehyde derivatives, anilines, coumarin-3- carboxylic acid and isocyanides with high yields and high bond-forming efficiency at room temperature. These novel amidated coumarins exhibit brilliant fluorescence in range of 535−547 nm in chloroform.

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  Cite this article

[IEEE Style]

E. Sheikhhosseini, S. Balalaie, M. A. Bigdeli, A. Habibi, H. P. Moghaddam, "Efficient Synthesis of Novel 3-Substituted Coumarin-3-carboxamide," Journal of the Korean Chemical Society, vol. 58, no. 2, pp. 186-192, 2014. DOI: 10.5012/jkcs.2014.58.2.186.

[ACM Style]

Enayatollah Sheikhhosseini, Saeed Balalaie, Mohammad Ali Bigdeli, Azizollah Habibi, and Hamed Piri Moghaddam. 2014. Efficient Synthesis of Novel 3-Substituted Coumarin-3-carboxamide. Journal of the Korean Chemical Society, 58, 2, (2014), 186-192. DOI: 10.5012/jkcs.2014.58.2.186.