Design, Synthesis and Antibacterial Activity Studies of Novel Quinoline Carboxamide Derivatives 


Vol. 57,  No. 2, pp. 241-245, Apr.  2013
10.5012/jkcs.2013.57.2.241


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  Abstract

A series of novel quinoline-6-carboxamides and 2-chloroquinoline-4-carboxamides were synthesized by the reaction of their analogous carboxylic acids with various amine derivatives in the presence of base TEA and protecting agent BOP at room temperature. Synthesized compounds were confirmed by spectral characterization viz IR, 1H-NMR, and MS. Antibacterial activity carried out against Escherichia coli and Staphyllococcus aureus indicated that the synthesized compounds were active against these microorganisms.

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  Cite this article

[IEEE Style]

Y. Shivaraj, M. H. Naveen, G. R. Vijayakumar, D. B. A. Kumar, "Design, Synthesis and Antibacterial Activity Studies of Novel Quinoline Carboxamide Derivatives," Journal of the Korean Chemical Society, vol. 57, no. 2, pp. 241-245, 2013. DOI: 10.5012/jkcs.2013.57.2.241.

[ACM Style]

Yellappa Shivaraj, Malenahalli H Naveen, Giriyapura R Vijayakumar, and Doyijode B Aruna Kumar. 2013. Design, Synthesis and Antibacterial Activity Studies of Novel Quinoline Carboxamide Derivatives. Journal of the Korean Chemical Society, 57, 2, (2013), 241-245. DOI: 10.5012/jkcs.2013.57.2.241.

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ISSN(Print) 1017-2548
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