Synthesis and Antibacterial Activity of Novel 5-(heteroaryl)isoxazole Derivatives 


Vol. 55,  No. 2, pp. 243-250, Apr.  2011
10.5012/jkcs.2011.55.2.243


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  Abstract

Isoxazole계 화합물을 합성하고 항균활성연구를 수행하였다. 3-Di(alkylamino)acryloalkanones을 hydroxylamine hydrochloride 또는 hydroxylamine-O-sulphonic acid와 반응시켜서 target isoxazole계 화합물을 합성하였다. The synthesis, characterization and antibacterial activity of novel isoxazole derivatives were reported. 3-Di (alkylamino)acryloalkanones were prepared and used as synthons to get the target isoxazole derivatives via reaction with hydroxylamine hydrochloride or hydroxylamine-O-sulphonic acid.

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  Cite this article

[IEEE Style]

R. J. RamaRao, A. K. S. B. Rao, N. Sreenivas, B. S. kumar, Y. L. N. Murthy, "Synthesis and Antibacterial Activity of Novel 5-(heteroaryl)isoxazole Derivatives," Journal of the Korean Chemical Society, vol. 55, no. 2, pp. 243-250, 2011. DOI: 10.5012/jkcs.2011.55.2.243.

[ACM Style]

R Janaki RamaRao, A K S Bhujanga Rao, N Sreenivas, B Suneel kumar, and Y L N Murthy. 2011. Synthesis and Antibacterial Activity of Novel 5-(heteroaryl)isoxazole Derivatives. Journal of the Korean Chemical Society, 55, 2, (2011), 243-250. DOI: 10.5012/jkcs.2011.55.2.243.

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