Design, Synthesis and Spectral Characterization of Novel 2-morpholino-N-(4,6-diarylpyrimidin-2-yl)acetamides 


Vol. 54,  No. 1, pp. 49-54, Feb.  2010
10.5012/jkcs.2010.54.1.049


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  Abstract

무수탄산칼륨 존재 하에서 2-chloro-N-(4,6-diarylpyrimidin-2-yl)acetamides 25-33를 모르포린과 축합 반응시켜서 2-morpholino-N-(4,6-diarylpyrimidin-2yl)acetamides 34-42 화합물들을 합성하였다. 합성된 화합물들의 녹는점, 원소분석, MS, FT-IR, 1H- & 13C-NMR로 화학적인 구조를 규명되었다. A new series of novel 2-morpholino-N-(4,6-diarylpyrimidin-2-yl)acetamides 34-42 is synthesized by the condensation of 2-chloro-N-(4,6-diarylpyrimidin-2-yl)acetamides 25-33 with morpholine in the presence of anhydrous potassium carbonate. The synthesized compounds have been characterized by melting point, elemental analysis, MS, FT-IR, one-dimensional NMR 1H &13C) spectroscopic data.

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  Cite this article

[IEEE Style]

V. Kanagarajan, J. Thanusu, M. Gopalakrishnan, "Design, Synthesis and Spectral Characterization of Novel 2-morpholino-N-(4,6-diarylpyrimidin-2-yl)acetamides," Journal of the Korean Chemical Society, vol. 54, no. 1, pp. 49-54, 2010. DOI: 10.5012/jkcs.2010.54.1.049.

[ACM Style]

Vijayakumar Kanagarajan, Jayaraman Thanusu, and Mannathusamy Gopalakrishnan. 2010. Design, Synthesis and Spectral Characterization of Novel 2-morpholino-N-(4,6-diarylpyrimidin-2-yl)acetamides. Journal of the Korean Chemical Society, 54, 1, (2010), 49-54. DOI: 10.5012/jkcs.2010.54.1.049.

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ISSN(Print) 1017-2548
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